ALDH8A1 antibody

Catalog No. ABIN7235787

The Rabbit Polyclonal anti-ALDH8A1 antibody is suitable to detect ALDH8A1 in samples from Human and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for ALDH8A1 antibody (ABIN7235787)

Target: ALDH8A1 (Aldehyde Dehydrogenase 8 Family, Member A1 (ALDH8A1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH8A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ALDH8A1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human ALDH8A1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ALDH8A1

Target: ALDH8A1 (Aldehyde Dehydrogenase 8 Family, Member A1 (ALDH8A1))

Alternative Name: ALDH8A1

Background: This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene.

Molecular Weight: 53 kDa

UniProt: Q9H2A2