FGFR1OP2 antibody

Catalog No. ABIN7236996

The Rabbit Polyclonal anti-FGFR1OP2 antibody (ABIN7236996) specifically detects FGFR1OP2 in ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FGFR1OP2 antibody (ABIN7236996)

Target: FGFR1OP2 (FGFR1 Oncogene Partner 2 (FGFR1OP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFR1OP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-FGFR1OP2 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human FGFR1OP2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FGFR1OP2

Target: FGFR1OP2 (FGFR1 Oncogene Partner 2 (FGFR1OP2))

Alternative Name: FGFR1OP2

Background: Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors which include the Flg receptor (FGFR-1) and the Bek receptor (FGFR-2), as well as FGFR-3, FGFR-4, FGFR-5 and FGFR-6. FGFR1OP2 (FGFR1 oncogene partner 2), also known as HSPC123, is a 253 amino acid cytoplasmic protein that is expressed in spleen, thymus and bone marrow and is involved in wound healing under normal cellular conditions. Additionally, FGFR1OP2 may also exist as an aberrant fusion protein with Flg and it is thought that the FGFR1OP2-Flg mutant may play a role in the pathogenesis of stem cell myeloproliferative disorder (MPD). Multiple isoforms of FGFR1OP2 exist due to alternative splicing events.

UniProt: Q9NVK5