HSD11B2 antibody
-
- Target See all HSD11B2 Antibodies
- HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This HSD11B2 antibody is un-conjugated
-
Application
- ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthetic peptide of human HSD11B2
- Isotype
- IgG
- Top Product
- Discover our top product HSD11B2 Primary Antibody
-
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 151-250) antibody
HSD11B2 Reactivity: Rat, Mouse, Horse WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) antibodyHSD11B2 Reactivity: Human, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 277-306) antibodyHSD11B2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB24535 unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-405) antibodyHSD11B2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 277-309), (C-Term) antibodyHSD11B2 Reactivity: Human, Rat, Mouse WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (N-Term) antibodyHSD11B2 Reactivity: Human, Rat, Mouse, Horse, Guinea Pig, Rabbit, Sheep, Cow WB Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 212-343) antibodyHSD11B2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 1-405) antibodyHSD11B2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (AA 284-314), (Middle Region) antibodyHSD11B2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2) (N-Term) antibodyHSD11B2 Reactivity: Human, Rat, Mouse, Guinea Pig, Rabbit, Sheep, Cow, Pig, Bat WB Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.6 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))
- Alternative Name
- HSD11B2 (HSD11B2 Products)
- Synonyms
- MGC81883 antibody, 11-HSD2 antibody, AME antibody, AME1 antibody, HSD11K antibody, HSD2 antibody, SDR9C3 antibody, 11HSD2 antibody, HSD11B2 antibody, hydroxysteroid (11-beta) dehydrogenase 2 L homeolog antibody, hydroxysteroid 11-beta dehydrogenase 2 antibody, hsd11b2.L antibody, HSD11B2 antibody, Hsd11b2 antibody
- Background
- There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor.
- NCBI Accession
- NP_000187
- UniProt
- P80365
- Pathways
- Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones
-
