NLRP4 antibody

Catalog No. ABIN7239236

This Rabbit Polyclonal antibody specifically detects NLRP4 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for NLRP4 antibody (ABIN7239236)

Target: NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-NLRP4 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human NLRP4

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NLRP4

Target: NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))

Alternative Name: NLRP4

Background: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes

NCBI Accession: NP_604393

UniProt: Q96MN2

Pathways: Inflammasome