DUSP12 antibody

Catalog No. ABIN7239899

The Rabbit Polyclonal anti-DUSP12 antibody has been validated for ELISA and IHC. It is suitable to detect DUSP12 in samples from Human, Mouse and Rat.

Quick Overview for DUSP12 antibody (ABIN7239899)

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP12 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-DUSP12 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human DUSP12

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DUSP12

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Alternative Name: DUSP12

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

UniProt: Q9UNI6

Pathways: Regulation of Carbohydrate Metabolic Process