AADAC antibody

Catalog No. ABIN7240373

The Rabbit Polyclonal anti-AADAC antibody has been validated for WB, ELISA and IHC. It is suitable to detect AADAC in samples from Human.

Quick Overview for AADAC antibody (ABIN7240373)

Target: AADAC (Arylacetamide Deacetylase (Esterase) (AADAC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AADAC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-AADAC Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human AADAC

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AADAC

Target: AADAC (Arylacetamide Deacetylase (Esterase) (AADAC))

Alternative Name: AADAC

Background: Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.

Molecular Weight: 46 kDa

UniProt: P22760