ADO antibody
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- Target See all ADO Antibodies
- ADO (2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ADO antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthetic peptide of human ADO
- Isotype
- IgG
- Top Product
- Discover our top product ADO Primary Antibody
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anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) antibody
ADO Reactivity: Human, Mouse, Rat WB, FACS Host: Rabbit Polyclonal unconjugated
anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) (AA 206-233), (C-Term) antibodyADO Reactivity: Human, Mouse WB, FACS Host: Rabbit Polyclonal RB30095 unconjugated
anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) (AA 137-270) antibodyADO Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO) (AA 206-233), (C-Term) antibodyADO Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:1000-1:5000, IHC 1:25-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.3 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ADO (2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO))
- Alternative Name
- ADO (ADO Products)
- Synonyms
- C10orf22 antibody, Gm237 antibody, RGD1308233 antibody, wu:fc32g01 antibody, wu:fc52c12 antibody, zgc:101580 antibody, 2-aminoethanethiol dioxygenase antibody, 2-aminoethanethiol (cysteamine) dioxygenase antibody, 2-aminoethanethiol (cysteamine) dioxygenase a antibody, ADO antibody, Ado antibody, LOC100351598 antibody, adoa antibody
- Background
- Human thiol dioxygenases include cysteine dioxygenase (CDO, MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO, EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine. Mouse Ado has strong and specific dioxygenase activity in vitro towards cysteamine but not cysteine. Recombinant Ado was shown to bind iron. Overexpression of Ado in HepG2/C3A cells increased the production of hypotaurine from cysteamine. Similar results were found with human ADO. When endogenous expression of ADO was reduced by RNA-mediated interference, hypotaurine production decreased. The demonstration of high levels of ADO in brain challenges the previous assumption that most of the taurine in the brain is a consequence of CDO activity.
- Molecular Weight
- 30 kDa
- NCBI Accession
- NP_116193
- UniProt
- Q96SZ5
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