INHBA antibody

Catalog No. ABIN7241993

Product Details anti-INHBA Antibody

Target: INHBA (Inhibin, beta A (INHBA))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INHBA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human INHBA

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for INHBA

Target: INHBA (Inhibin, beta A (INHBA))

Alternative Name: INHBA (INHBA Products)

Synonyms: EDF antibody, FRP antibody, actba antibody, inhba antibody, inhbaa-001 antibody, edf antibody, frp antibody, INHB antibody, inhbal antibody, zgc:158348 antibody, inhibin beta A subunit antibody, inhibin beta-A antibody, inhibin, beta Aa antibody, inhibin beta A antibody, inhibin, beta Ab antibody, INHBA antibody, Inhba antibody, inhbaa antibody, inhba antibody, inhbab antibody

Background: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Molecular Weight: 47 kDa

NCBI Accession: NP_002183

UniProt: P08476

Pathways: Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy