Afadin antibody

Catalog No. ABIN7242503

This Rabbit Polyclonal antibody specifically detects Afadin in ELISA and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Afadin antibody (ABIN7242503)

Target: Afadin (MLLT4)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Afadin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-Afadin Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human MLLT4

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Afadin

Target: Afadin (MLLT4)

Alternative Name: AFDN

Background: This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6,11)(q27,q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.

NCBI Accession: NP_001035089

UniProt: P55196

Pathways: Cell-Cell Junction Organization