AMZ1
Reactivity: Human
Host: Rabbit
Polyclonal
Alexa Fluor 647
Application Notes
WB 1:500-1:2000, IHC 1:50-1:200
Restrictions
For Research Use only
Format
Liquid
Concentration
1.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
AMZ1
(Archaelysin Family Metallopeptidase 1 (AMZ1))
Alternative Name
AMZ1
Background
AMZ1shares sequence similarity with archaeal metalloproteases called archaemetzincins, but it appears to act predominantly as a basic aminopeptidase. Inhibited by the general metalloprotease inhibitors o-phenanthroline and batimastat. Also significantly inhibited by amastatin, which is an inhibitor of aminopeptidases. Not inhibited by 4-(2-aminoethyl)-benzenesulfonyl fluoride, E-64, and TIMPS (tissue inhibitors of metalloproteinases), which are inhibitors of serine, cysteine, and matrix metalloproteases, respectively.