DEFA4 antibody

Catalog No. ABIN7243241

The Rabbit Polyclonal anti-DEFA4 antibody (ABIN7243241) specifically detects DEFA4 in IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for DEFA4 antibody (ABIN7243241)

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEFA4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-DEFA4 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human DEFA4

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DEFA4

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Alternative Name: DEFA4

Background: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils, it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production.

NCBI Accession: NP_001916

UniProt: P12838