PPOX antibody
Quick Overview for PPOX antibody (ABIN7243778)
Target
See all PPOX AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Synthetic peptide of human PPOX
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Isotype
- IgG
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Application Notes
- WB 1:1000-1:5000, IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- PPOX (Protoporphyrinogen Oxidase (PPOX))
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Alternative Name
- PPOX
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Background
- This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
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Molecular Weight
- 51 kDa
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NCBI Accession
- NP_000300
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UniProt
- P50336
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Pathways
- Synaptic Membrane, Feeding Behaviour
Target
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