TCEB1 antibody

Catalog No. ABIN7244036

The Rabbit Polyclonal anti-TCEB1 antibody is suitable to detect TCEB1 in samples from Human, Mouse and Rat. It has been validated for ELISA and IHC.

Quick Overview for TCEB1 antibody (ABIN7244036)

Target: TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEB1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-TCEB1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Full length fusion protein

Isotype: IgG

Application Details

Application Notes: IHC 1:30-150, ELISA 1:2000-10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TCEB1

Target: TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))

Alternative Name: ELOC

Background: This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.

UniProt: Q15369

Pathways: SARS-CoV-2 Protein Interactome