VPS33B antibody

Catalog No. ABIN7244204

The Rabbit Polyclonal anti-VPS33B antibody (ABIN7244204) specifically detects VPS33B in ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for VPS33B antibody (ABIN7244204)

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS33B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-VPS33B Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Fusion protein of human VPS33B

Isotype: IgG

Application Details

Application Notes: IHC 1:30-150, ELISA 1:2000-10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for VPS33B

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Alternative Name: VPS33B

Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants.

UniProt: Q9H267