CA5B antibody

Catalog No. ABIN7244609

The Rabbit Polyclonal anti-CA5B antibody (ABIN7244609) specifically detects CA5B in IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for CA5B antibody (ABIN7244609)

Target: CA5B (Carbonic Anhydrase VB, Mitochondrial (CA5B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA5B antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-CA5B Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human CA5B

Isotype: IgG

Application Details

Application Notes: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CA5B

Target: CA5B (Carbonic Anhydrase VB, Mitochondrial (CA5B))

Alternative Name: CA5B

Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.CA5B (Carbonic Anhydrase 5B) is a Protein Coding gene. Diseases associated with CA5B include Heart Conduction Disease and Heart Septal Defect. Among its related pathways are Nitrogen metabolism and Metabolism. GO annotations related to this gene include carbonate dehydratase activity. An important paralog of this gene is CA5A.

UniProt: Q9Y2D0