PPY antibody

Catalog No. ABIN7245389

This Rabbit Polyclonal antibody specifically detects PPY in WB and ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for PPY antibody (ABIN7245389)

Target: PPY (Pancreatic Polypeptide (PPY))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPY antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PPY Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human PPY

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 3 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPY

Target: PPY (Pancreatic Polypeptide (PPY))

Alternative Name: PPY

Background: This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 11 kDa

UniProt: P01298

Pathways: Feeding Behaviour