ZNF486 antibody

Catalog No. ABIN7245794

Product Details anti-ZNF486 Antibody

Target: ZNF486 (Zinc Finger Protein 486 (ZNF486))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF486 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human ZNF486

Isotype: IgG

Application Details

Application Notes: IHC 1:40-1:250, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZNF486

Target: ZNF486 (Zinc Finger Protein 486 (ZNF486))

Alternative Name: ZNF486 (ZNF486 Products)

Synonyms: KRBO2 antibody, zinc finger protein 486 antibody, ZNF486 antibody

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF486 (Zinc finger protein 486), also known as KRAB domain only protein 2, is a 216 amino acid nuclear protein that contains one KRAB domain and two C2H2-type zinc fingers. The gene encoding ZNF486 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. May be involved in transcriptional regulation.

UniProt: Q96H40