WDFY2 antibody

Catalog No. ABIN7245935

Product Details anti-WDFY2 Antibody

Target: WDFY2 (ZFYVE22) (Zinc Finger, FYVE Domain Containing 22 (ZFYVE22))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDFY2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human WDFY2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WDFY2

Target: WDFY2 (ZFYVE22) (Zinc Finger, FYVE Domain Containing 22 (ZFYVE22))

Alternative Name: WDFY2 (ZFYVE22 Products)

Synonyms: PROF antibody, RP11-147H23.1 antibody, WDF2 antibody, ZFYVE22 antibody, 5830485M08 antibody, B130024L21Rik antibody, ProF antibody, WD repeat and FYVE domain-containing protein 2 antibody, WD repeat and FYVE domain containing 2 antibody, wdfy-2 antibody, WDFY2 antibody, Wdfy2 antibody

Background: WD repeat and FYVE domain-containing protein 2 (WDFY2), also known as WDF2 and ZFYVE22, is a 400 amino acid protein that localizes to a set of small endosomes that are found within 100 nm from the plasma membrane. Highly conserved between species, WDFY2 consists of one FYVE-type zinc finger and seven WD repeats. The FYVE domain is a cysteine-rich domain of about 70 amino acids. Its primary role is to target signal-transducing proteins to cell membranes through binding to the membrane lipid phosphatidylinositol-3-phosphate with high specificity. WD-repeats are generally found in clusters of seven. They have no intrinsic catalytic activity, but they serve as a platform for protein-protein interactions. WDFY2 is suspected to play a critical role in the endocytic pathway.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 45 kDa

UniProt: Q96P53