MCPH1 antibody

Catalog No. ABIN7246046

Product Details anti-MCPH1 Antibody

Target: MCPH1 (Microcephalin 1 (MCPH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCPH1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human MCPH1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MCPH1

Target: MCPH1 (Microcephalin 1 (MCPH1))

Alternative Name: MCPH1 (MCPH1 Products)

Synonyms: RGD1560642 antibody, MGC83773 antibody, MCPH1 antibody, mct antibody, brit1 antibody, MGC148665 antibody, BRIT1 antibody, MCT antibody, 5430437K10Rik antibody, D030046N04Rik antibody, microcephalin 1 antibody, microcephalin 1 S homeolog antibody, microcephaly, primary autosomal recessive 1 antibody, Mcph1 antibody, mcph1.S antibody, MCPH1 antibody, mcph1 antibody

Background: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

UniProt: Q8NEM0

Pathways: Stem Cell Maintenance