CUTA antibody

Catalog No. ABIN7246193

Product Details anti-CUTA Antibody

Target: CUTA (Protein CutA (CUTA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUTA antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human CUTA

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CUTA

Target: CUTA (Protein CutA (CUTA))

Alternative Name: CUTA (CUTA Products)

Synonyms: ACHAP antibody, C6orf82 antibody, 0610039D01Rik antibody, 1810022E02Rik antibody, 1810060C03Rik antibody, 2700094G22Rik antibody, AI326454 antibody, CutA1 antibody, cutA divalent cation tolerance homolog antibody, CUTA antibody, Cuta antibody

Background: CUTA, also known as ACHAP (acetylcholinesterase-associated protein), is the 179 amino acid mammalian homolog of the cutA E. coli protein and is ubiquitously expressed, particularly in brain tissue. Existing as multiple alternatively spliced isoforms, CUTA functions as a homotrimer that is thought to act as a component of an acetylcholinesterase (AChE)-attached complex, suggesting an involvement in AChE regulation. The gene encoding CUTA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6 % of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

UniProt: O60888