TMX3 antibody

Catalog No. ABIN7247537

The Rabbit Polyclonal anti-TMX3 antibody (ABIN7247537) specifically detects TMX3 in ELISA and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for TMX3 antibody (ABIN7247537)

Target: TMX3 (Thioredoxin-Related Transmembrane Protein 3 (TMX3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMX3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-TMX3 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human TMX3

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.26 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TMX3

Target: TMX3 (Thioredoxin-Related Transmembrane Protein 3 (TMX3))

Alternative Name: TMX3

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

UniProt: Q96JJ7

Pathways: Cell RedoxHomeostasis