GLI1 antibody
-
- Target See all GLI1 Antibodies
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GLI1 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human GLI1
- Isotype
- IgG
- Top Product
- Discover our top product GLI1 Primary Antibody
-
-
- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.08 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
- Alternative Name
- GLI1 (GLI1 Products)
- Background
- GLI1 (GLI Family Zinc Finger 1) is a Protein Coding gene. Diseases associated with GLI1 include Basal Cell Carcinoma and Necrobiosis Lipoidica. Among its related pathways are Wnt Signaling Pathways: beta-Catenin-independent Wnt/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways and G-Beta Gamma Signaling. GO annotations related to this gene include chromatin binding and microtubule binding. An important paralog of this gene is GLI2. This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
-
Observed_MW: Refer to figures
Calculated_MW: 118 kDa
- UniProt
- P08151
- Pathways
- Hedgehog Signaling, Dopaminergic Neurogenesis
-