UBAC2 antibody

Catalog No. ABIN7248272

Product Details anti-UBAC2 Antibody

Target: UBAC2 (UBA Domain Containing 2 (UBAC2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBAC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human UBAC2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UBAC2

Target: UBAC2 (UBA Domain Containing 2 (UBAC2))

Alternative Name: UBAC2 (UBAC2 Products)

Synonyms: UBAC2 antibody, phgdhl1 antibody, MGC185596 antibody, PHGDHL1 antibody, 1190008A14Rik antibody, AW554959 antibody, Phgdhl1 antibody, UBA domain containing 2 antibody, ubiquitin associated domain containing 2 antibody, UBAC2 antibody, ubac2 antibody, Ubac2 antibody

Background: UBAC2 (ubiquitin-associated domain-containing protein 2), also known as PHGDHL1 (phosphoglycerate dehydrogenase-like protein 1), is a 344 amino acid multi-pass membrane protein that contains one UBA domain and is expressed as multiple alternatively spliced isoforms. The gene encoding UBAC2 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4 % of the human genome. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 39 kDa

UniProt: Q8NBM4