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CORO2B antibody

CORO2B Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7248476
  • Target See all CORO2B Antibodies
    CORO2B (Coronin, Actin Binding Protein, 2B (CORO2B))
    Reactivity
    • 30
    • 13
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 27
    • 2
    • 1
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CORO2B antibody is un-conjugated
    Application
    • 21
    • 14
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human CORO2B
    Isotype
    IgG
  • Application Notes
    WB 1:1000-1:5000, IHC 1:40-1:200, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.5 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CORO2B (Coronin, Actin Binding Protein, 2B (CORO2B))
    Alternative Name
    CORO2B (CORO2B Products)
    Synonyms
    CLIPINC antibody, E130012P22Rik antibody, CORO2B antibody, coro2b antibody, Coronin-2B antibody, coronin 2B antibody, coronin, actin binding protein, 2B antibody, coronin, actin binding protein, 2Ba antibody, coronin-2B antibody, coronin, actin binding protein, 2B L homeolog antibody, CORO2B antibody, Coro2b antibody, coro2b antibody, coro2ba antibody, LOC100342263 antibody, coro2b.L antibody
    Background
    Coronins are a family of WD repeat-containing, actin-binding proteins that localize to submembraneous areas and regulate cell motility and cytoskeletal rearrangement. Coronin 1A (CORO1A, CLIPINA, CLABP, TACO, p57) can form coiled coil-mediated homotrimeric complexes that influence early phagosome formation. PKC-dependent phosphorylation of Coronin 1B (CORO1B) at Serine 2 regulates leading edge dynamics and cell motility in fibroblasts through interactions with Arp2/3 complex. Coronin 1C (CORO1C, Coronin 3, HCRNN4) is abundant in differentiating Neuro-2a cells, PC-12 cells and primary oligodendrocytes, where it is thought to influence neuron morphogenesis and migration. Coronin 2A (CORO2A, CLIPINB, IR10, WDR2) is a component of the approximately 1.5-2 megadalton N-CoR (nuclear receptor corepressor) complex of 10-12 proteins, which recruits HDACs to generate repressive chromatin. Coronin 7 (CORO7, CRN7) localizes to the Golgi membrane and influences the organization of intracellular membrane compartments and vesicular trafficking. Coronin 2B (CORO2B, CLIPINC) and Coronin 6 (CORO6) are similar to other members of this family, since they possess a conserved basic N-terminal motif and 3-10 WD repeats clustered in one to two core domains.
    Molecular Weight

    Observed_MW: Refer to figures

    Calculated_MW: 55 kDa

    UniProt
    Q9UQ03
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