ZIC2 antibody

Catalog No. ABIN7249346

This Rabbit Polyclonal antibody specifically detects ZIC2 in ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for ZIC2 antibody (ABIN7249346)

Target: ZIC2

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZIC2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-ZIC2 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human ZIC2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, ELISA 1:2000-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZIC2

Target: ZIC2

Alternative Name: ZIC2

Background: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.

UniProt: O95409

Pathways: Tube Formation