CD11c antibody

Catalog No. ABIN7249394

The Rabbit Polyclonal anti-CD11c antibody is suitable to detect CD11c in samples from Human, Mouse and Rat. It has been validated for IHC, WB and IF.

Quick Overview for CD11c antibody (ABIN7249394)

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD11c antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CD11c Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CD11c

Isotype: IgG

Application Details

Application Notes: WB1:500-1:1000, IHC 1:100-1:300, IF 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.98 mg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD11c

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Alternative Name: ITGAX

Background: Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a type I transmembrane protein present on a variety of cells,including monocytes/macrophages,granulocytes,NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis.

Molecular Weight:

Observed_MW: 150 kDa

Calculated_MW: 120-150 kDa

UniProt: P20702, Q9QXH4

Pathways: Complement System, Activated T Cell Proliferation, Integrin Complex