Cytokeratin 7 antibody

Catalog No. ABIN7249868

This Mouse Monoclonal antibody specifically detects Cytokeratin 7 in WB and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Cytokeratin 7 antibody (ABIN7249868)

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 7D8G8

Product Details anti-Cytokeratin 7 Antibody

Characteristics: Monoclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse Cytokeratin 7

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.8 mg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cytokeratin 7

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Alternative Name: CK-7

Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells,which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins,including K9-K23,and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins,including K1-K8,and the hair keratins,Hb1-Hb6. KRT7,also named as cytokeratin 7,is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels,and their neoplasms. KRT7 is marker of epithelial tissues,but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7.

Molecular Weight:

Observed_MW: 51 kDa

Calculated_MW: 51 kDa

UniProt: P08729, Q9DCV7, Q6IG12