BMP2 antibody

Catalog No. ABIN7249966

The Mouse Monoclonal anti-BMP2 antibody has been validated for IHC. It is suitable to detect BMP2 in samples from Rat.

Quick Overview for BMP2 antibody (ABIN7249966)

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This BMP2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: 2H6D12

Product Details anti-BMP2 Antibody

Characteristics: Monoclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse BMP2

Isotype: IgG

Application Details

Application Notes: IHC 1:200-1:800

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.65 mg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Alternative Name: BMP2

Background: Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer, 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction.

UniProt: P12643, P21274, P49001

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation