FGFR4 antibody (pTyr642)
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- Target See all FGFR4 Antibodies
- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
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Binding Specificity
- pTyr642
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FGFR4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Characteristics
- Phosphorylated antibody
- Purification
- Affinity purification
- Immunogen
- Synthesized peptide derived from human FGFR-4 around the phosphorylation site of Tyr642
- Isotype
- IgG
- Top Product
- Discover our top product FGFR4 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, ELISA 1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
- Alternative Name
- FGFR4 (FGFR4 Products)
- Synonyms
- FGFR4 antibody, XFGFR-4 antibody, XFGFR-4a antibody, cd334 antibody, fgfr-4 antibody, jtk2 antibody, tkf antibody, xfgfr4 antibody, CD334 antibody, JTK2 antibody, TKF antibody, Fgfr-4 antibody, etID309818.21 antibody, wu:fc13h10 antibody, zgc:111935 antibody, fgfr-4c antibody, fgfr4 antibody, fibroblast growth factor receptor 4 antibody, fibroblast growth factor receptor 4 S homeolog antibody, FGFR4 antibody, fgfr4 antibody, Fgfr4 antibody, fgfr4.S antibody
- Background
- The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. FGFR4 (Fibroblast Growth Factor Receptor 4) is a Protein Coding gene. Diseases associated with FGFR4 include Prostate Cancer and Neuroma. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is FGFR3.
- Molecular Weight
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Observed_MW: 90 kDa
Calculated_MW: 88 kDa
- UniProt
- P22455
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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