Dystrobrevin beta antibody (AA 261-370) (Biotin)

Catalog No. ABIN700632

This anti-Dystrobrevin beta antibody is a Rabbit Polyclonal antibody detecting Dystrobrevin beta in ELISA, IHC (p) and IHC (fro). Suitable for Human and Rat.

Quick Overview for Dystrobrevin beta antibody (AA 261-370) (Biotin) (ABIN700632)

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dystrobrevin beta antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Dystrobrevin beta Antibody (Biotin)

Binding Specificity: AA 261-370

Specificity: This antibody may cross-react with DTNA based upon a 75 % sequence similarity across the immunogen sequence range.

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DTNB

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Dystrobrevin beta

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Alternative Name: DTNB

Background:

Synonyms: Dystrobrevin beta, DTN-B, Beta-dystrobrevin, DTNB

Background: Dystrobrevin beta is a component of the dystrophin-associated protein complex and interacts with dystrophin short form DP71, syntrophins SNTG1 and SNTG2. It localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. 4 isoforms produced by alternative splicing have been identified.

Gene ID: 1838

UniProt: O60941