Dystrobrevin beta antibody (AA 261-370) (HRP)

Catalog No. ABIN700639

This Rabbit Polyclonal antibody specifically detects Dystrobrevin beta in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Rat.

Quick Overview for Dystrobrevin beta antibody (AA 261-370) (HRP) (ABIN700639)

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dystrobrevin beta antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Dystrobrevin beta Antibody (HRP)

Binding Specificity: AA 261-370

Specificity: This antibody may cross-react with DTNA based upon a 75 % sequence similarity across the immunogen sequence range.

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DTNB

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Dystrobrevin beta

Target: Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))

Alternative Name: DTNB

Background:

Synonyms: Dystrobrevin beta, DTN-B, Beta-dystrobrevin, DTNB

Background: Dystrobrevin beta is a component of the dystrophin-associated protein complex and interacts with dystrophin short form DP71, syntrophins SNTG1 and SNTG2. It localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. 4 isoforms produced by alternative splicing have been identified.

Gene ID: 1838

UniProt: O60941