PPP1R3C antibody

Catalog No. ABIN7253284

Product Details anti-PPP1R3C Antibody

Target: PPP1R3C (Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R3C antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human PPP1R3C

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPP1R3C

Target: PPP1R3C (Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C))

Alternative Name: PPP1R3C (PPP1R3C Products)

Synonyms: PPP1R5 antibody, PTG antibody, Ppp1r5 antibody, R5 antibody, ppp1r3c antibody, zgc:73259 antibody, protein phosphatase 1 regulatory subunit 3C antibody, protein phosphatase 1, regulatory (inhibitor) subunit 3C antibody, protein phosphatase 1, regulatory subunit 3C antibody, protein phosphatase 1, regulatory subunit 3Cb antibody, PPP1R3C antibody, Ppp1r3c antibody, ppp1r3cb antibody, ppp1r3c antibody

Background: This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease.

UniProt: Q9UQK1

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process