TNNT1 antibody

Catalog No. ABIN7254007

The Rabbit Polyclonal anti-TNNT1 antibody has been validated for WB, IHC and ELISA. It is suitable to detect TNNT1 in samples from Human and Mouse.

Quick Overview for TNNT1 antibody (ABIN7254007)

Target: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-TNNT1 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human TNNT1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:50, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.66 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TNNT1

Target: TNNT1 (Slow Skeletal Troponin T (TNNT1))

Alternative Name: TNNT1

Background: This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 33 kDa

UniProt: P13805