HTRA1 antibody
Quick Overview for HTRA1 antibody (ABIN7254340)
Target
See all HTRA1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human HTRA1
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.9 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
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Alternative Name
- HTRA1
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Background
- This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.
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Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 51 kDa
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UniProt
- Q92743
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Pathways
- Growth Factor Binding
Target
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