SASH1 antibody
Quick Overview for SASH1 antibody (ABIN7254376)
Target
See all SASH1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human SASH1
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.78 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- SASH1 (SAM and SH3 Domain Containing 1 (SASH1))
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Alternative Name
- SASH1
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Background
- This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients.
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Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 137 kDa
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UniProt
- O94885
Target
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