MAFA antibody

Catalog No. ABIN7254463

This Rabbit Polyclonal antibody specifically detects MAFA in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for MAFA antibody (ABIN7254463)

Target: MAFA (Transcription Factor MafA (MAFA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAFA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MAFA Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human MAFA

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAFA

Target: MAFA (Transcription Factor MafA (MAFA))

Alternative Name: MAFA

Background: Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 37 kDa

UniProt: Q8NHW3

Pathways: Hormone Transport