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YBX1 antibody
YBX1
Reactivity: Human, Rat, Mouse
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-YBX1 Antibody
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Target
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YBX1
(Y Box Binding Protein 1 (YBX1))
Reactivity
All reactivities for YBX1 antibodies
Human, Rat, Mouse
Host
All hosts for YBX1 antibodies
Rabbit
Clonality
All clonalities for YBX1 antibodies
Polyclonal
Conjugate
All conjugates for YBX1 antibodies
This YBX1 antibody is un-conjugated
Application
All applications for YBX1 antibodies
ELISA, Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Antigen affinity purification
Immunogen
Synthetic peptide of human YBX1
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IHC 1:30-1:150, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.6 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for YBX1
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Target
YBX1
(Y Box Binding Protein 1 (YBX1))
Alternative Name
YBX1 (YBX1 Products )
Synonyms
BP-8 antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, MDR-NF1 antibody, NSEP-1 antibody, NSEP1 antibody, YB-1 antibody, YB1 antibody, Byb1 antibody, Cbfa antibody, Dbpb antibody, Ef1a antibody, Msy1 antibody, Nsep1 antibody, Yb1 antibody, bp-8 antibody, csda2 antibody, csdb antibody, dbpb antibody, frgy1 antibody, mdr-nf1 antibody, nsep-1 antibody, nsep1 antibody, yb1 antibody, 1700102N10Rik antibody, C79409 antibody, EF1A antibody, MSY1 antibody, dbpB antibody, mYB-1a antibody, nuclease sensitive element binding protein 1 antibody, Y-box binding protein 1 antibody, Y box binding protein 1 antibody, Y-box binding protein 1 S homeolog antibody, nuclease-sensitive element-binding protein 1 antibody, Y box protein 1 antibody, nsep1 antibody, YBX1 antibody, Ybx1 antibody, ybx1.S antibody, LOC479011 antibody
Background
This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).
UniProt
P67809
Pathways
Regulation of Muscle Cell Differentiation
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