HSD17B1 antibody
-
- Target See all HSD17B1 Antibodies
- HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))
-
Reactivity
- Human, Rat, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This HSD17B1 antibody is un-conjugated
-
Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human HSD17B1 (NP_000404.2).
- Isotype
- IgG
- Top Product
- Discover our top product HSD17B1 Primary Antibody
-
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 189-285) antibody
HSD17B1 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 2E5 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 1-328) antibodyHSD17B1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 29-43), (N-Term) antibodyHSD17B1 Reactivity: Human, Rat WB, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 29-43) antibodyHSD17B1 Reactivity: Human, Rat, Mouse WB, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 4-289) antibodyHSD17B1 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 2-261) antibodyHSD17B1 Reactivity: Human WB, ELISA, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 268-328) antibodyHSD17B1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (AA 21-120) antibodyHSD17B1 Reactivity: Human, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) antibodyHSD17B1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1) (N-Term) antibodyHSD17B1 Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Pig, Guinea Pig, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- IHC 1:50-1:200 IF 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))
- Alternative Name
- HSD17B1 (HSD17B1 Products)
- Synonyms
- EDH17B2 antibody, EDHB17 antibody, HSD17 antibody, SDR28C1 antibody, 17HSDB1 antibody, 17beta-HSD antibody, E2DH antibody, Hsd17ba antibody, 17BHD1 antibody, zfHSD17B1 antibody, hydroxysteroid 17-beta dehydrogenase 1 antibody, hydroxysteroid (17-beta) dehydrogenase 1 antibody, HSD17B1 antibody, Hsd17b1 antibody, hsd17b1 antibody
- Background
- Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.
- Gene ID
- 3292
- UniProt
- P14061
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
-
