BAX antibody
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- Target See all BAX Antibodies
- BAX (BCL2-Associated X Protein (BAX))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BAX antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- This antibody ist KO validated.
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Grade
- KO Validated
- Immunogen
- A synthetic peptide of human BAX (NP_620116.1).
- Isotype
- IgG
- Top Product
- Discover our top product BAX Primary Antibody
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anti-BCL2-Associated X Protein (BAX) (AA 84-175) antibody
BAX Reactivity: Human, Mouse, Rat, Pig, Cow, Rabbit, Chicken, Zebrafish (Danio rerio) WB, ELISA, FACS, IP, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-100) antibodyBAX Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibodyBAX Reactivity: Human, Mouse WB, FACS Host: Rabbit Polyclonal RB0952 unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX Reactivity: Human, Mouse, Rat, Monkey, Pig, Cow, Rabbit, Dog, Chicken, Sheep, Horse, Guinea Pig, Hamster, Goat, Avian, Cat, Donkey WB, IF Host: Goat Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-158) antibodyBAX Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX Reactivity: Human ELISA, IHC, FACS Host: Mouse Monoclonal 2D8H2 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibodyBAX Reactivity: Human ELISA, IHC Host: Mouse Monoclonal 4H9B11 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 2G6B2 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibodyBAX Reactivity: Human WB, ELISA, IF, IHC (p), PLA Host: Mouse Monoclonal 1F5-1B7 unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX Reactivity: Human, Pig, Cow, Dog WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000 IHC 1:100-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- BAX (BCL2-Associated X Protein (BAX))
- Alternative Name
- BAX (BAX Products)
- Background
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
- Molecular Weight
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Observed_MW: 20 kDa
Calculated_MW: 4 kDa/12 kDa/15 kDa/18 kDa/19 kDa/21 kDa/24 kDa
- Gene ID
- 581
- UniProt
- Q07812
- Pathways
- p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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