GEMIN8 antibody

Catalog No. ABIN7257325

The Rabbit Polyclonal anti-GEMIN8 antibody has been validated for WB. It is suitable to detect GEMIN8 in samples from Human.

Quick Overview for GEMIN8 antibody (ABIN7257325)

Target: GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEMIN8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GEMIN8 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human GEMIN8 (NP_060326.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GEMIN8

Target: GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))

Alternative Name: GEMIN8

Background: The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.

Molecular Weight:

Observed_MW: 35 kDa

Calculated_MW: 28 kDa

Gene ID: 54960

UniProt: Q9NWZ8

Pathways: Ribonucleoprotein Complex Subunit Organization