ATP6V1G3i antibody

Catalog No. ABIN7257870

The Rabbit Polyclonal anti-ATP6V1G3i antibody (ABIN7257870) specifically detects ATP6V1G3i in WB and IHC. The antibody is reactive with Mouse samples.

Quick Overview for ATP6V1G3i antibody (ABIN7257870)

Target: ATP6V1G3i (ATP6V1G3) (ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G3 (ATP6V1G3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1G3i antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ATP6V1G3i Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human ATP6V1G3 (NP_573569.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATP6V1G3i

Target: ATP6V1G3i (ATP6V1G3) (ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G3 (ATP6V1G3))

Alternative Name: ATP6V1G3

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 14 kDa

Calculated_MW: 6 kDa/13 kDa/14 kDa

Gene ID: 127124

UniProt: Q96LB4

Pathways: Transition Metal Ion Homeostasis, Proton Transport