ATP6V1G3i antibody (AA 1-118)

Catalog No. ABIN7265759

Product Details anti-ATP6V1G3i Antibody

Target: ATP6V1G3i (ATP6V1G3) (ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G3 (ATP6V1G3))

Binding Specificity: AA 1-118

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1G3i antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: ATP6V1G3 Rabbit pAb

Sequence: MTSQSQGIHQ LLQAEKRAKD KLEEAKKRKG KRLKQAKEEA MVEIDQYRMQ RDKEFRLKQS KIMGSQNNLS DEIEEQTLGK IQELNGHYNK YMESVMNQLL SMVCDMKPEI HVNYRATN

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human ATP6V1G3 (NP_573569.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATP6V1G3i

Target: ATP6V1G3i (ATP6V1G3) (ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G3 (ATP6V1G3))

Alternative Name: ATP6V1G3 (ATP6V1G3 Products)

Synonyms: ATP6G3 antibody, Vma10 antibody, ATPase H+ transporting V1 subunit G3 antibody, ATPase, H+ transporting, lysosomal V1 subunit G3 antibody, ATP6V1G3 antibody, Atp6v1g3 antibody

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene.,ATP6V1G3,ATP6G3,Vma10,Cancer,Signal Transduction,Endocrine & Metabolism,ATP6V1G3

Molecular Weight: 6kDa/13kDa/14kDa

Gene ID: 127124

UniProt: Q96LB4

Pathways: Transition Metal Ion Homeostasis, Proton Transport