PLEKHA1 antibody

Catalog No. ABIN7258834

The Rabbit Polyclonal anti-PLEKHA1 antibody is suitable to detect PLEKHA1 in samples from Human. It has been validated for IF.

Quick Overview for PLEKHA1 antibody (ABIN7258834)

Target: PLEKHA1 (Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEKHA1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-PLEKHA1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PLEKHA1 (NP_067635.2).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLEKHA1

Target: PLEKHA1 (Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1))

Alternative Name: PLEKHA1

Background: This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.

Gene ID: 59338

UniProt: Q9HB21

Pathways: Platelet-derived growth Factor Receptor Signaling