CXCR1 antibody

Catalog No. ABIN7259098

This anti-CXCR1 antibody is a Rabbit Polyclonal antibody detecting CXCR1 in WB and IHC. Suitable for Human, Rat and Mouse.

Quick Overview for CXCR1 antibody (ABIN7259098)

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CXCR1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human CXCR1 (NP_000625.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CXCR1

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Alternative Name: CXCR1

Background: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

Molecular Weight:

Observed_MW: 70 kDa

Calculated_MW: 39 kDa

Gene ID: 3577

UniProt: P25024

Pathways: cAMP Metabolic Process