HSD3B2 antibody

Catalog No. ABIN7009767

The Rabbit Polyclonal anti-HSD3B2 antibody has been validated for WB and IF. It is suitable to detect HSD3B2 in samples from Human and Mouse.

Quick Overview for HSD3B2 antibody (ABIN7009767)

Target: HSD3B2 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD3B2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-HSD3B2 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human HSD3B2 (NP_000189.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HSD3B2

Target: HSD3B2 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2))

Alternative Name: HSD3B2

Background: The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight:

Observed_MW: 47 kDa

Calculated_MW: 24 kDa/42 kDa

Gene ID: 3284

UniProt: P26439

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis