GRB14 antibody
Quick Overview for GRB14 antibody (ABIN7260633)
Target
See all GRB14 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of human GRB14
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Isotype
- IgG
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Application Notes
- WB 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
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Alternative Name
- GRB14
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Background
- The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.
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Molecular Weight
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Observed_MW: 61 kDa
Calculated_MW: 51 kDa/60 kDa
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Gene ID
- 2888
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UniProt
- Q14449
Target
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