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GALC antibody

The Rabbit Polyclonal anti-GALC antibody has been validated for WB and IHC. It is suitable to detect GALC in samples from Human, Rat and Mouse.
Catalog No. ABIN7260891

Quick Overview for GALC antibody (ABIN7260891)

Target

See all GALC Antibodies
GALC (Galactosylceramidase (GALC))

Reactivity

  • 38
  • 24
  • 22
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Rat, Mouse

Host

  • 43
  • 3
Rabbit

Clonality

  • 43
  • 3
Polyclonal

Conjugate

  • 21
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GALC antibody is un-conjugated

Application

  • 37
  • 10
  • 10
  • 7
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Characteristics

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogen

    Recombinant fusion protein of human GALC (NP_000144.2).

    Isotype

    IgG
  • Application Notes

    WB 1:500-1:2000 IHC 1:50-1:100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    GALC (Galactosylceramidase (GALC))

    Alternative Name

    GALC

    Background

    This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Molecular Weight

    Observed_MW: 77 kDa

    Calculated_MW: 67 kDa/74 kDa/77 kDa

    Gene ID

    2581

    UniProt

    P54803
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