KIFAP3 antibody

Catalog No. ABIN7261082

The Rabbit Polyclonal anti-KIFAP3 antibody (ABIN7261082) specifically detects KIFAP3 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for KIFAP3 antibody (ABIN7261082)

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIFAP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KIFAP3 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human KIFAP3 (NP_055785.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KIFAP3

Target: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Alternative Name: KIFAP3

Background: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 110 kDa

Calculated_MW: 82 kDa/86 kDa/91 kDa

Gene ID: 22920

UniProt: Q92845

Pathways: Hedgehog Signaling, Sensory Perception of Sound