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PLA2G1B antibody

This Rabbit Polyclonal antibody specifically detects PLA2G1B in WB and IHC. It exhibits reactivity toward Human and Mouse.
Catalog No. ABIN7261439

Quick Overview for PLA2G1B antibody (ABIN7261439)

Target

See all PLA2G1B Antibodies
PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

Reactivity

  • 32
  • 17
  • 9
  • 6
  • 4
  • 4
Human, Mouse

Host

  • 40
  • 5
  • 1
Rabbit

Clonality

  • 42
  • 4
Polyclonal

Conjugate

  • 27
  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PLA2G1B antibody is un-conjugated

Application

  • 38
  • 23
  • 12
  • 9
  • 8
  • 7
  • 6
  • 6
  • 6
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • Characteristics

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogen

    Recombinant fusion protein of human PLA2G1B (NP_000919.1).

    Isotype

    IgG
  • Application Notes

    WB 1:500-1:2000 IHC 1:100-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))

    Alternative Name

    PLA2G1B

    Background

    This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.

    Molecular Weight

    Observed_MW: 16 kDa

    Calculated_MW: 16 kDa

    Gene ID

    5319

    UniProt

    P04054

    Pathways

    Inositol Metabolic Process, VEGF Signaling
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