COMP antibody

Catalog No. ABIN7261762

The Rabbit Polyclonal anti-COMP antibody (ABIN7261762) specifically detects COMP in WB and IF. The antibody is reactive with Mouse, Human and Rat samples.

Quick Overview for COMP antibody (ABIN7261762)

Target: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-COMP Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human COMP (NP_000086.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COMP

Target: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Alternative Name: COMP

Background: The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

Molecular Weight:

Observed_MW: 110 kDa

Calculated_MW: 77 kDa/82 kDa

Gene ID: 1311

UniProt: P49747